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Rescue of the Adeno-Associated Virus Genome from a Plasmid Vector: Evidence for Rescue by Replication

In cultured cells, adeno-associated virus (AAV) replication requires coinfection with a helper virus, either adenovirus or herpesvirus. In the absence of helper virus coinfection AAV can integrate its genome site specifically into the AAVS1 region of chromosome 19. Upon subsequent infection with a h...

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Autori principali: Ward, Peter, Elias, Per, Linden, R. Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC229372/
https://ncbi.nlm.nih.gov/pubmed/14557633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11480-11490.2003
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