טוען...

Importance of Protease Cleavage Sites within and Flanking Human Immunodeficiency Virus Type 1 Transframe Protein p6* for Spatiotemporal Regulation of Protease Activation

The human immunodeficiency virus type 1 (HIV-1) protease (PR) has recently been shown to be inhibited by its propeptide p6* in vitro. As p6* itself is a PR substrate, the primary goal of this study was to determine the importance of p6* cleavage for HIV-1 maturation and infectivity. For that purpose...

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מידע ביבליוגרפי
Main Authors: Ludwig, Christine, Leiherer, Andreas, Wagner, Ralf
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293064/
https://ncbi.nlm.nih.gov/pubmed/18321978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02353-07
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