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The Interaction of Herpes Simplex Virus 1 Regulatory Protein ICP22 with the cdc25C Phosphatase Is Enabled In Vitro by Viral Protein Kinases U(S)3 and U(L)13

Earlier studies have shown that ICP22 and the U(L)13 protein kinase but not the U(S)3 kinase are required for optimal expression of a subset of late (γ(2)) genes exemplified by U(L)38, U(L)41, and U(S)11. In primate cells, ICP22 mediates the disappearance of inactive isoforms of cdc2 and degradation...

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Detalhes bibliográficos
Main Authors: Smith-Donald, Benjamin A., Roizman, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293044/
https://ncbi.nlm.nih.gov/pubmed/18272572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02022-07
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