Two Amino Acid Substitutions within the First External Loop of CCR5 Induce Human Immunodeficiency Virus-Blocking Antibodies in Mice and Chickens

Antibodies to the first loop (ECL1) of CCR5 have been identified in human immunodeficiency virus (HIV)-exposed uninfected individuals (ESN) and in HIV-positive nonprogressing subjects. Thus, these antibodies may confer resistance against HIV infection. To define which amino acids are involved in ant...

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Main Authors: Pastori, Claudia, Clivio, Alberto, Diomede, Lorenzo, Consonni, Roberto, De Mori, Giacomo M. S., Longhi, Renato, Colombo, Giorgio, Lopalco, Lucia
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293020/
https://ncbi.nlm.nih.gov/pubmed/18256149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02232-07
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