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Human CAR Gene Expression in Nonpermissive Hamster Cells Boosts Entry of Type 12 Adenovirions and Nuclear Import of Viral DNA

Adenovirus type 12 (Ad12) propagation in hamster BHK21 cells is blocked prior to viral DNA replication. The amounts of Ad12 DNA in the nuclei or cytoplasm of hamster cells are about 2 orders of magnitude (2 h postinfection [p.i.]) and 4 to 5 orders of magnitude (48 h p.i.) lower than in permissive h...

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Detalhes bibliográficos
Main Authors: Hochstein, Norbert, Webb, Dennis, Hösel, Marianna, Seidel, Werner, Auerochs, Sabrina, Doerfler, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293008/
https://ncbi.nlm.nih.gov/pubmed/18256153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02657-07
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