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Human CAR Gene Expression in Nonpermissive Hamster Cells Boosts Entry of Type 12 Adenovirions and Nuclear Import of Viral DNA

Adenovirus type 12 (Ad12) propagation in hamster BHK21 cells is blocked prior to viral DNA replication. The amounts of Ad12 DNA in the nuclei or cytoplasm of hamster cells are about 2 orders of magnitude (2 h postinfection [p.i.]) and 4 to 5 orders of magnitude (48 h p.i.) lower than in permissive h...

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Bibliografske podrobnosti
Main Authors: Hochstein, Norbert, Webb, Dennis, Hösel, Marianna, Seidel, Werner, Auerochs, Sabrina, Doerfler, Walter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293008/
https://ncbi.nlm.nih.gov/pubmed/18256153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02657-07
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