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Human CAR Gene Expression in Nonpermissive Hamster Cells Boosts Entry of Type 12 Adenovirions and Nuclear Import of Viral DNA

Adenovirus type 12 (Ad12) propagation in hamster BHK21 cells is blocked prior to viral DNA replication. The amounts of Ad12 DNA in the nuclei or cytoplasm of hamster cells are about 2 orders of magnitude (2 h postinfection [p.i.]) and 4 to 5 orders of magnitude (48 h p.i.) lower than in permissive h...

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Библиографические подробности
Главные авторы: Hochstein, Norbert, Webb, Dennis, Hösel, Marianna, Seidel, Werner, Auerochs, Sabrina, Doerfler, Walter
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293008/
https://ncbi.nlm.nih.gov/pubmed/18256153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02657-07
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