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Lineage-specific responses to reduced embryonic Pax3 expression levels
Pax3 is an essential paired- and homeodomain-containing transcription factor that is necessary for closure of the neural tube,, and morphogenesis of the migratory neural crest and myoblast lineages. Homozygous loss-of-function mutation results in mid-gestational lethality with defects in myogenesis,...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292838/ https://ncbi.nlm.nih.gov/pubmed/18243171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.12.020 |
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