Topography and chemical reactivity of the active–inactive transition-sensitive SH-group in the mitochondrial NADH:ubiquinone oxidoreductase (Complex I)

The spatial arrangement and chemical reactivity of the activation-dependent thiol in the mitochondrial Complex I was studied using the membrane penetrating N-ethylmaleimide (NEM) and non-penetrating anionic 5,5′-dithiobis-(2-nitrobenzoate) (DTNB) as the specific inhibitors of the enzyme in mitochond...

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Main Authors: Gostimskaya, Irina S., Cecchini, Gary, Vinogradov, Andrei D.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292829/
https://ncbi.nlm.nih.gov/pubmed/16777054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2006.04.016
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