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LDL-cholesterol concentrations: a genome-wide association study

BACKGROUND: LDL cholesterol has a causal role in the development of cardiovascular disease. Improved understanding of the biological mechanisms that underlie the metabolism and regulation of LDL cholesterol might help to identify novel therapeutic targets. We therefore did a genome-wide association...

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Detalhes bibliográficos
Main Authors: Sandhu, Manjinder S, Waterworth, Dawn M, Debenham, Sally L, Wheeler, Eleanor, Papadakis, Konstantinos, Zhao, Jing Hua, Song, Kijoung, Yuan, Xin, Johnson, Toby, Ashford, Sofie, Inouye, Michael, Luben, Robert, Sims, Matthew, Hadley, David, McArdle, Wendy, Barter, Philip, Kesäniemi, Y Antero, Mahley, Robert W, McPherson, Ruth, Grundy, Scott M, Bingham, Sheila A, Khaw, Kay-Tee, Loos, Ruth JF, Waeber, Gérard, Barroso, Inês, Strachan, David P, Deloukas, Panagiotis, Vollenweider, Peter, Wareham, Nicholas J, Mooser, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Lancet Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292820/
https://ncbi.nlm.nih.gov/pubmed/18262040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(08)60208-1
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