HLA Class II Haplotypes Distinctly Associated with Vaso-Occlusion in Children with Sickle Cell Disease

We investigated the association of HLA class II alleles and haplotypes with sickle cell anemia vaso-occlusive crisis (VOC). DRB1*100101 was positively associated, while DRB1*140101, DRB1*150101, and DQB1*060101 were negatively associated, with VOC. Both susceptible (DRB1*100101-DQB1*050101) and prot...

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Detalhes bibliográficos
Main Authors: Mahdi, Najat, Al-Ola, Khadija, Al-Subaie, Abeer M., Ali, Muhallab E., Al-Irhayim, Zaid, Al-Irhayim, A. Qader, Almawi, Wassim Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Immune Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292664/
https://ncbi.nlm.nih.gov/pubmed/18272668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00425-07
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