Modulation of Type 1 Diabetes Susceptibility by Tumor Necrosis Factor Alpha −308 G/A and Lymphotoxin Alpha +249 A/G Haplotypes and Lack of Linkage Disequilibrium with Predisposing DQB1-DRB1 Haplotypes in Bahraini Patients

Tumor necrosis factor alpha (TNF-α) −308 G/A and lymphotoxin alpha (LTα) +249 A/G single-nucleotide polymorphisms were investigated in 228 type 1 diabetes mellitus (T1DM) patients and 240 controls. Only LTα +249G allele and +249G/+249G genotype frequencies were higher among patients, and no linkage...

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Autores principales: Stayoussef, Mouna, Al-Jenaidi, Fayza A., Al-Abbasi, Abduljabbar, Al-Ola, Khadija, Khayyat, Haya, Mahjoub, Touhami, Almawi, Wassim Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Materias:
Cellular Immunology, Antibodies, and Mediators of Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238059/
https://ncbi.nlm.nih.gov/pubmed/17989340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00410-07
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