Multigene DNA Priming-Boosting Vaccines Protect Macaques from Acute CD4(+)-T-Cell Depletion after Simian-Human Immunodeficiency Virus SHIV89.6P Mucosal Challenge

We evaluated four priming-boosting vaccine regimens for the highly pathogenic simian human immunodeficiency virus SHIV89.6P in Macaca nemestrina. Each regimen included gene gun delivery of a DNA vaccine expressing all SHIV89.6 genes plus Env gp160 of SHIV89.6P. Additional components were two recombi...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Doria-Rose, N. A., Ohlen, C., Polacino, P., Pierce, C. C., Hensel, M. T., Kuller, L., Mulvania, T., Anderson, D., Greenberg, P. D., Hu, S.-L., Haigwood, N. L.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2003
Предметы:	Vaccines and Antiviral Agents
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11563-11577.2003
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