Slowly Declining Levels of Viral RNA and DNA in DNA/Recombinant Modified Vaccinia Virus Ankara-Vaccinated Macaques with Controlled Simian-Human Immunodeficiency Virus SHIV-89.6P Challenges

In a recent vaccine trial, we showed efficient control of a virulent simian-human immunodeficiency virus SHIV-89.6P challenge by priming with a Gag-Pol-Env-expressing DNA and boosting with a Gag-Pol-Env- expressing recombinant-modified vaccinia virus Ankara. Here we show that long-term control has b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tang, Yuyang, Villinger, Francois, Staprans, Silvija I., Amara, Rama Rao, Smith, James M., Herndon, James G., Robinson, Harriet L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136570/
https://ncbi.nlm.nih.gov/pubmed/12239289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10147-10154.2002
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