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Drug-Regulated Expression of Plasmodium falciparum P-Glycoprotein Homologue 1: a Putative Role for Nuclear Receptors

Acquired resistance to therapeutic agents is a major clinical concern in the prevention/treatment of malaria. The parasite has developed resistance to specific drugs through two mechanisms: mutations in target proteins such as dihydrofolate reductase and the bc1 complex for antifolates and nathoquin...

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Hlavní autoři: Johnson, David J., Owen, Andrew, Plant, Nick, Bray, Patrick G., Ward, Stephen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292565/
https://ncbi.nlm.nih.gov/pubmed/18195056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01392-07
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