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Larger Vancomycin Doses (at Least Four Grams per Day) Are Associated with an Increased Incidence of Nephrotoxicity
Recent guidelines recommend vancomycin trough concentrations between 15 and 20 mg/liter. In response, some clinicians increased vancomycin dosing to ≥4 g/day. Scant data are available regarding toxicities associated with higher vancomycin doses. The purpose of this study was to examine vancomycin-as...
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Главные авторы: | , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Microbiology (ASM)
2008
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292536/ https://ncbi.nlm.nih.gov/pubmed/18227177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01602-07 |
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