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Characterization of a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, A-790742
A-790742 is a potent human immunodeficiency virus type 1 (HIV-1) protease inhibitor, with 50% effective concentrations ranging from 2 to 7 nM against wild-type HIV-1. The activity of this compound is lowered by approximately sevenfold in the presence of 50% human serum. A-790742 maintained potent an...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292532/ https://ncbi.nlm.nih.gov/pubmed/18212102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01132-07 |
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