Drosomycin-Like Defensin, a Human Homologue of Drosophila melanogaster Drosomycin with Antifungal Activity

Innate antifungal defense in Drosophila melanogaster relies on the activation of the Toll molecule and the release of drosomycin, a defensin-like molecule with antifungal properties. Ten human homologues of Toll have been described, with central roles in activation of the innate host defense. In the...

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Detalhes bibliográficos
Main Authors: Simon, Anna, Kullberg, Bart Jan, Tripet, Brian, Boerman, Otto C., Zeeuwen, Patrick, van der Ven-Jongekrijg, Johanna, Verweij, Paul, Schalkwijk, Joost, Hodges, Robert, van der Meer, Jos W. M., Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292511/
https://ncbi.nlm.nih.gov/pubmed/18212107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00155-07
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