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Diallyl disulphide depletes glutathione in Candida albicans: oxidative stress-mediated cell death studied by two-photon microscopy

Using two-photon scanning laser microscopy, we investigated the effect of an Allium sativum (garlic) constituent, diallyl disulphide (DADS), on key physiological functions of the opportunistic pathogen Candida albicans. A short 30 min exposure to 0.5 mm DADS followed by removal induced 70% cell deat...

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Detalhes bibliográficos
Main Authors: Lemar, Katey M., Aon, Miguel A., Cortassa, Sonia, O’Rourke, Brian, T. Müller, Carsten, Lloyd, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292485/
https://ncbi.nlm.nih.gov/pubmed/17534841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/yea.1503
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