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UVB-induced apoptosis drives clonal expansion during skin tumor development
The mechanism by which a single mutant cell clonally expands is usually assumed to involve an additional mutation in a cell cycle regulatory gene. An alternative mechanism for driving clonal expansion is apoptosis, which might create vacant stem cell compartments that can be repopulated by mutant ce...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292404/ https://ncbi.nlm.nih.gov/pubmed/15498793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgh300 |
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