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Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin
Melanin protects the skin against DNA damage induced by direct absorption of sunlight's UV radiation. Yet, irradiating melanin in vitro or in cultured cells also generates active oxygen species such as superoxide, which can indirectly induce oxidative base lesions and DNA strand breaks. This ph...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524044/ https://ncbi.nlm.nih.gov/pubmed/15477596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403994101 |
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