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Effects of Surface Water on Protein Dynamics Studied by a Novel Coarse-Grained Normal Mode Approach

Normal mode analysis (NMA) has received much attention as a direct approach to extract the collective motions of macromolecules. However, the stringent requirement of computational resources by classical all-atom NMA limits the size of the macromolecules to which the method is normally applied. We i...

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Bibliographic Details
Main Authors: Zhou, Lei, Siegelbaum, Steven A.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292380/
https://ncbi.nlm.nih.gov/pubmed/18212016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115956
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