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Development of a whole blood intracellular cytokine staining assay for mapping CD4(+) and CD8(+) T-cell responses across the HIV-1 genome

A whole blood peptide mapping intracellular cytokine staining (ICS) assay was developed that allows the direct comparison, at the individual peptide level, of CD4(+) and CD8(+) T-cell responses that span every encoded protein, in patients infected with HIV-1. Whole blood samples from HIV-1 infected...

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Autores principales: Meddows-Taylor, Stephen, Shalekoff, Sharon, Kuhn, Louise, Gray, Glenda E., Tiemessen, Caroline T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292247/
https://ncbi.nlm.nih.gov/pubmed/17543395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2007.04.004
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