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Gene placement and competition control T cell receptor γ variable region gene rearrangement

The production of distinct sets of T cell receptor (TCR) γδ(+) T cells occurs in an ordered fashion in thymic development. The Vγ3 and Vγ4 genes, located downstream in the TCRγ Cγ1 gene cluster, are expressed by the earliest waves of developing TCRγδ(+) T cells in the fetal thymus, destined for intr...

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Bibliografiske detaljer
Main Authors: Xiong, Na, Zhang, Li, Kang, Chulho, Raulet, David H.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292229/
https://ncbi.nlm.nih.gov/pubmed/18378791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071275
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