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Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity

Histone deacetylases such as human HDAC1 and yeast RPD3 are trichostatin A (TSA)-sensitive enzymes that are members of large, multiprotein complexes. These contain specialized subunits that help target the catalytic protein to histones at the appropriate DNA regulatory element, where the enzyme repr...

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Autori principali: Carmen, Andrew A., Griffin, Patrick R., Calaycay, Jimmy R., Rundlett, Stephen E., Suka, Yuko, Grunstein, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22921/
https://ncbi.nlm.nih.gov/pubmed/10535926
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