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3α-Hydroxysteroid Dehydrogenase Type III Deficiency: A Novel Mechanism for Hirsutism
Context: Dihydrotestosterone (DHT), the primary active androgen in peripheral target tissues, is metabolized by 3α-hydroxysteroid dehydrogenase type III (3α-HSD), encoded by the AKR1C2 gene, forming 5α-androstane-3α,17β-diol (3α-diol). 3α-HSD may play a role in the pathogenesis of hirsutism. Objecti...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Endocrine Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291485/ https://ncbi.nlm.nih.gov/pubmed/18252781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-2708 |
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