Structural and functional characterization of a novel acidophilic 7α‐hydroxysteroid dehydrogenase

7α‐Hydroxysteroid dehydrogenase (7α‐HSDH) is an NAD(P)H‐dependent oxidoreductase belonging to the short‐chain dehydrogenases/reductases. In vitro, 7α‐HSDH is involved in the efficient biotransformation of taurochenodeoxycholic acid (TCDCA) to tauroursodeoxycholic acid (TUDCA). In this study, a gene...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Tang, Shijin, Pan, Yinping, Lou, Deshuai, Ji, Shunlin, Zhu, Liancai, Tan, Jun, Qi, Na, Yang, Qiong, Zhang, Zhi, Yang, Biling, Zhao, Wenyan, Wang, Bochu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
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Full‐Length Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460000/
https://ncbi.nlm.nih.gov/pubmed/30839141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3599
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