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G1/S Cyclin-dependent Kinase Regulates Small GTPase Rho1p through Phosphorylation of RhoGEF Tus1p in Saccharomyces cerevisiae

Rho1p is an essential small GTPase that plays a key role in the morphogenesis of Saccharomyces cerevisiae. We show here that the activation of Rho1p is regulated by a cyclin-dependent kinase (CDK). Rho1p is activated at the G1/S transition at the incipient-bud sites by the Cln2p (G1 cyclin) and Cdc2...

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Autores principales: Kono, Keiko, Nogami, Satoru, Abe, Mitsuhiro, Nishizawa, Masafumi, Morishita, Shinichi, Pellman, David, Ohya, Yoshikazu
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291405/
https://ncbi.nlm.nih.gov/pubmed/18256282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-09-0950
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