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Assembly of a catalytic unit for RNA microhelix aminoacylation using nonspecific RNA binding domains

An assembly of a catalytic unit for aminoacylation of an RNA microhelix is demonstrated here. This assembly may recapitulate a step in the historical development of tRNA synthetases. The class-defining domain of a tRNA synthetase is closely related to the primordial enzyme that catalyzed synthesis o...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Chihade, Joseph W., Schimmel, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535919/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12316
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