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Assembly of a catalytic unit for RNA microhelix aminoacylation using nonspecific RNA binding domains

An assembly of a catalytic unit for aminoacylation of an RNA microhelix is demonstrated here. This assembly may recapitulate a step in the historical development of tRNA synthetases. The class-defining domain of a tRNA synthetase is closely related to the primordial enzyme that catalyzed synthesis o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chihade, Joseph W., Schimmel, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22914/
https://ncbi.nlm.nih.gov/pubmed/10535919
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