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Pharmacokinetics and tolerability of voriconazole and a combination oral contraceptive co-administered in healthy female subjects

AIM: To assess the two-way pharmacokinetic interaction between voriconazole and Ortho-Novum® 1/35, an oral contraceptive containing norethindrone 1 mg and ethinyl oestradiol 35 μg. METHODS: In this open-label, three-period, fixed-sequence study, 16 healthy females received voriconazole (400 mg q12 h...

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Detalhes bibliográficos
Main Authors: Andrews, Emma, Damle, Bharat D, Fang, Annie, Foster, Grover, Crownover, Penelope, LaBadie, Robert, Glue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291369/
https://ncbi.nlm.nih.gov/pubmed/18294327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03084.x
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