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Increased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese mice

Low-grade systemic inflammation, as indicated by increased circulating levels of inflammatory markers CRP and IL-6, is linked to increased risks for cardiovascular diseases (CVD) and diabetes mellitus in obese subjects. Whereas hyperleptinemia in obesity are associated with increased CRP and IL-6 re...

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Bibliografske podrobnosti
Main Authors: Dube, Michael G., Torto, Rita, Kalra, Satya P.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291149/
https://ncbi.nlm.nih.gov/pubmed/18325632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.01.001
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