Postendocytotic traffic of the galanin R1 receptor: A lysosomal signal motif on the cytoplasmic terminus

The neuropeptide galanin R1 receptor (GalR1) was tagged at its C terminus with EGFP (GalR1–EGFP) to study receptor localization and trafficking. In PC12 and HEK293 cells, functional GalR1–EGFP was expressed on the plasma membrane and internalized into cytoplasmic vesicles after galanin stimulation....

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Bibliographic Details
Main Authors: Xia, Sheng, Dun, Xing-Peng, Hu, Ping-Sheng, Kjaer, Svend, Zheng, Kang, Qian, Yu, Solén, Christina, Xu, Tao, Fredholm, Bertil, Hökfelt, Tomas, Xu, Zhi-Qing David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291124/
https://ncbi.nlm.nih.gov/pubmed/18385373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801456105
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