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Postendocytotic traffic of the galanin R1 receptor: A lysosomal signal motif on the cytoplasmic terminus

The neuropeptide galanin R1 receptor (GalR1) was tagged at its C terminus with EGFP (GalR1–EGFP) to study receptor localization and trafficking. In PC12 and HEK293 cells, functional GalR1–EGFP was expressed on the plasma membrane and internalized into cytoplasmic vesicles after galanin stimulation....

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Bibliografske podrobnosti
Main Authors: Xia, Sheng, Dun, Xing-Peng, Hu, Ping-Sheng, Kjaer, Svend, Zheng, Kang, Qian, Yu, Solén, Christina, Xu, Tao, Fredholm, Bertil, Hökfelt, Tomas, Xu, Zhi-Qing David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291124/
https://ncbi.nlm.nih.gov/pubmed/18385373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801456105
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