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Postendocytotic traffic of the galanin R1 receptor: A lysosomal signal motif on the cytoplasmic terminus

The neuropeptide galanin R1 receptor (GalR1) was tagged at its C terminus with EGFP (GalR1–EGFP) to study receptor localization and trafficking. In PC12 and HEK293 cells, functional GalR1–EGFP was expressed on the plasma membrane and internalized into cytoplasmic vesicles after galanin stimulation....

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Autores principales: Xia, Sheng, Dun, Xing-Peng, Hu, Ping-Sheng, Kjaer, Svend, Zheng, Kang, Qian, Yu, Solén, Christina, Xu, Tao, Fredholm, Bertil, Hökfelt, Tomas, Xu, Zhi-Qing David
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291124/
https://ncbi.nlm.nih.gov/pubmed/18385373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801456105
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