A comprehensive modular map of molecular interactions in RB/E2F pathway

We present, here, a detailed and curated map of molecular interactions taking place in the regulation of the cell cycle by the retinoblastoma protein (RB/RB1). Deregulations and/or mutations in this pathway are observed in most human cancers. The map was created using Systems Biology Graphical Notat...

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Autori principali: Calzone, Laurence, Gelay, Amélie, Zinovyev, Andrei, Radvanyi, François, Barillot, Emmanuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290939/
https://ncbi.nlm.nih.gov/pubmed/18319725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.7
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