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Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi- derived COP-coated vesicles

The cycle of nucleotide exchange and hydrolysis by a small GTP-binding protein, ADP-ribosylation factor (ARF), helps to provide vectoriality to vesicle transport. Coat assembly is triggered when ARF binds GTP, initiating transport vesicle budding, and coat disassembly is triggered when ARF hydrolyze...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290881/
https://ncbi.nlm.nih.gov/pubmed/8253837
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