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Conformational basis for the Li(+)-induced leak current in the rat γ-aminobutyric acid (GABA) transporter-1
The rat γ-aminobutyric acid transporter-1 (GAT-1) was expressed in Xenopus laevis oocytes and the substrate-independent Li(+)-induced leak current was examined using two-electrode voltage clamp. The leak current was not affected by the addition of GABA and was not due to H(+) permeation. The Li(+)-b...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290608/ https://ncbi.nlm.nih.gov/pubmed/12381817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.022897 |
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