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Binding site stoichiometry and the effects of phosphorylation on human α1 homomeric glycine receptors

The kinetic properties of the human α1 homomeric glycine receptor were investigated. Receptors were expressed in HEK 293 cells, and glycine was applied to outside-out membrane patches with sub-millisecond solution exchange. The activation time course of the glycine response was used to investigate r...

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Autori principali: Gentet, Luc J, Clements, John D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290580/
https://ncbi.nlm.nih.gov/pubmed/12356883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.015321
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