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Myofilament-based relaxant effect of isoprenaline revealed during work-loop contractions in rat cardiac trabeculae

In cardiac muscle, β-adrenergic stimulation increases contractile force and accelerates relaxation. The relaxant effect is thought to be due primarily to stimulation of Ca(2+) uptake into the sarcoplasmic reticulum (SR), although changes in myofilament properties may also contribute. The present stu...

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Detalhes bibliográficos
Main Authors: Layland, Joanne, Kentish, Jonathan C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290578/
https://ncbi.nlm.nih.gov/pubmed/12356890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.022855
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