Effects of Mg(2+) and SR luminal Ca(2+) on caffeine-induced Ca(2+) release in skeletal muscle from humans susceptible to malignant hyperthermia

Regulation of the ryanodine receptor (RYR) by Mg(2+) and SR luminal Ca(2+) was studied in mechanically skinned malignant hyperthermia susceptible (MHS) and non-susceptible (MHN) fibres from human vastus medialis. Preparations were perfused with solutions mimicking the intracellular milieu and change...

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Bibliographische Detailangaben
Hauptverfasser: Duke, Adrian M, Hopkins, Philip M, Steele, Derek S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2002
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290564/
https://ncbi.nlm.nih.gov/pubmed/12356882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.022749
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