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Cellular mechanisms for apical ATP effects on intracellular pH in human bronchial epithelium

The effect of external ATP on intracellular pH (pH(i)) was investigated using a pH imaging system in a human bronchial epithelial cell line (16HBE14o-) loaded with BCECF-AM. The steady-state pH(i) of 16HBE14o- epithelial monolayers was 7.137 ± 0.027 (n = 46). Apical addition of ATP (10(−4)m) to epit...

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Autori principali: Urbach, V, Hélix, N, Renaudon, B, Harvey, B J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290491/
https://ncbi.nlm.nih.gov/pubmed/12181278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.015180
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