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Modulation by permeant ions of Mg(2+) inhibition of NMDA-activated whole-cell currents in rat cortical neurons

Whole-cell N-methyl-d-aspartate (NMDA)-activated currents were recorded from cultured rat cortical neurons. We report here a powerful effect of changing permeant ion concentrations on the voltage-dependent inhibition by external Mg(2+) (Mg(2+) ([Formula: see text]) of these currents. Internal Cs(+)...

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Détails bibliographiques
Auteurs principaux: Qian, Anqi, Antonov, Sergei M, Johnson, Jon W
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290035/
https://ncbi.nlm.nih.gov/pubmed/11773317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.012685
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