Llwytho...

Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice

Current anticancer therapy is a delicate balance between elimination of malignant cells and harmful side effects for the host. In this study, we used a tumor-homing peptide to engineer anti-CD40 agonist antibodies and recombinant IL-2 such that they were selectively delivered into spontaneously aris...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hamzah, Juliana, Nelson, Delia, Moldenhauer, Gerd, Arnold, Bernd, Hämmerling, Günter J., Ganss, Ruth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289791/
https://ncbi.nlm.nih.gov/pubmed/18398504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33201
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