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Functional dissection of the phosphorylated termini of fission yeast DNA topoisomerase II

Fission Yeast DNA topoisomerase II (165 kD) consists of an enzymatically active 125-kD core, approximately 10-kD NH2-terminal and 30-kD COOH-terminal domains. The question addressed in the present study is what is the role of the topo II termini. Although deletion of either the NH2 or the COOH termi...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289710/
https://ncbi.nlm.nih.gov/pubmed/1332977
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