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Low nitric oxide: a key factor underlying copper deficiency teratogenicity

Copper (Cu) deficiency-induced teratogenicity is characterized by major cardiac, brain and vascular anomalies, however, the underlying mechanisms are poorly understood. Cu deficiency decreases superoxide dismutase activity, and increases superoxide anions which can interact with nitric oxide (NO), r...

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Bibliografiske detaljer
Main Authors: Yang, Soo Jin, Keen, Carl L., Lanoue, Louise, Rucker, Robert B., Uriu-Adams, Janet Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289431/
https://ncbi.nlm.nih.gov/pubmed/18037129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.08.031
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