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Low nitric oxide: a key factor underlying copper deficiency teratogenicity

Copper (Cu) deficiency-induced teratogenicity is characterized by major cardiac, brain and vascular anomalies, however, the underlying mechanisms are poorly understood. Cu deficiency decreases superoxide dismutase activity, and increases superoxide anions which can interact with nitric oxide (NO), r...

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Detalhes bibliográficos
Main Authors: Yang, Soo Jin, Keen, Carl L., Lanoue, Louise, Rucker, Robert B., Uriu-Adams, Janet Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289431/
https://ncbi.nlm.nih.gov/pubmed/18037129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.08.031
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