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Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils

The ability of cultured human fibroblasts to reorganize and contract three dimensional collagen I gels is regarded as an in vitro model for the reorganization of connective tissue during wound healing. We investigated whether adhesion receptors of the integrin family are involved. It was found that...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289246/
https://ncbi.nlm.nih.gov/pubmed/1955483
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