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ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells

We have used compactin, an inhibitor of mevalonate biosynthesis, to block p21ras posttranslational modification and membrane association in PC12 cells. Previous studies have demonstrated a requirement for isoprenylation for mitogenic effects of activated p21ras in mammalian cells and for function of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 1991
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289192/
https://ncbi.nlm.nih.gov/pubmed/1918164
Tagiau: Ychwanegu Tag
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