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ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells
We have used compactin, an inhibitor of mevalonate biosynthesis, to block p21ras posttranslational modification and membrane association in PC12 cells. Previous studies have demonstrated a requirement for isoprenylation for mitogenic effects of activated p21ras in mammalian cells and for function of...
Gorde:
| Formatua: | Artigo |
|---|---|
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
1991
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2289192/ https://ncbi.nlm.nih.gov/pubmed/1918164 |
| Etiketak: |
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