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Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol

Diphtheria toxin belongs to a group of toxic proteins that enter the cytosol of animal cells. We have here investigated the effect of NH2- terminal extensions of diphtheria toxin on its ability to become translocated to the cytosol. DNA fragments encoding peptides of 12-30 amino acids were fused by...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289021/
https://ncbi.nlm.nih.gov/pubmed/2040642
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